Randy Wendelin's HAART Attack

by David Pasquarelli

 

Editor's Note: This piece is about, not by its subject, actor Rany Wendelin. It came to us as is from its author, David Pasquarelli of Act UP San Francisco. Date of posting is 8/20/01.


Did you see that San Francisco's Bay Area Reporter paid homage in the Arts 
section of their most recent issue to actor and porn star Randy Wendelin, who 
lost his life last week to coronary arrest? It was reported that the 
HIV-positive Wendelin, once a buff bodybuilder and avid promoter of 
experimental protease inhibitors, had a sudden heart attack and unexpectedly 
died in the arms of his lover. No doubt the obituary will announce this poor 
soul died of "AIDS," but at this point I think we all know better. AIDS drugs 
were the real killer.

You see, I remember Randy Wendelin. Scowling at Ronnie Burk on Market Street 
near the Castro. Throwing objects at Michael Petrelis during a Stop AIDS 
Project forum where Petrelis criticized the fraud inherent in AIDS funding. 
Or looking drawn and deformed at meetings of the San Francisco HIV Prevention 
Planning Council as he attacked members of ACT UP San Francisco for pointing 
out the deadly effects of protease inhibitors.

There's no denying Randy Wendelin sacrificed his body to the great AIDS drug 
experiment and lost. Even as the pills he popped destroyed and deformed him 
he defended them by publicly pronouncing that: "Working out burns off fat 
everywhere, so that if your body fat is low, lipodystrophy makes you even 
leaner. It's not this terrible, tragic disease. I get hired because I have 
character in my face. Losing facial fat can make a man more handsome."

Sure, it does. Look where AIDS drugs and the consequent lipodystrophy got 
him. His handsome face is now buried six feet under in a pretty pine box. 
Talk about denial!

No, I didn't like Randy Wendelin. He was a particularly shallow member of the 
vain and vapid Castro white-boy elite. But now he's dead. And it makes me 
realize that, love him or loathe him, he was a human being with talents and 
gifts that didn't deserve to be poisoned to death. He had family and friends 
that cared about him. Like all of us, he deserved to live a life free from 
terror, exploitation, and destruction at the greedy hands of AIDS Inc.

Included below are two media clippings from 1999 and 2000 featuring the words 
of dead Randy Wendelin. He was no special martyr. Just another sad victim of 
AIDS drug poisoning. One that makes me wonder how much longer we as a gay 
community are expected to endure this monstrous HIV madness...

David Pasquarelli
ACT UP SF

=====

San Francisco Frontiers
August 24, 2000

Waste Not, Want Not
-----
Fat, Physique, Face and HIV

By Carlton Elliott Smith
Photos by Tom Bianchi

Cecilia Chung could see and touch the places where her body was warping. She 
gained three inches on her waistline without altering her diet. Conscious of 
her image, she was working out harder than ever to get back to her shapely 
figure but with no success. At the same time, she was losing fat on her face 
and arms and legs, causing her to look much less healthy than she felt. "For 
a while, it was really depressing to see my body changing right before my 
face," she says.

At the time, Chung, who is HIV-positive, was taking three anti-retroviral 
medications including D4T, more commonly known as Zerit, which some doctors 
believe causes lipodystrophy, a syndrome of abnormal fat distribution. Her 
symptoms were classic -- fat wasting in the face and the extremities and fat 
accumulation in the abdomen, in the breasts of women and, in rare cases, in 
the neck, sometimes called a "buffalo hump." She had many talks with her 
doctor about what she could do to reverse the condition. As a transgender 
woman taking hormones, she was ineligible for drug trials. She switched to a 
different drug cocktail, taking Ziagen, Sustiva and Epivir.

After developing a mysterious rash while on that last regimen, Chung went on 
a structured treatment interruption, taking no anti-retroviral medications, 
starting last October. Over the months, she's seen and felt improvements: her 
digestion has become normal again and her body fat has started to 
redistribute itself. "I got my waistline back," she says. "I still have 
losses of subcutaneous fat in my arms and legs, but it's not as noticeable 
because my body is more proportionate."

Chung is hardly alone in negotiating the wasting that is a common side effect 
of living with HIV/AIDS and the medications used to treat it. Throughout the 
Bay Area and beyond, people living with HIV/AIDS and their physicians are 
seeking to understand lipodystrophy and the best ways to respond to its 
effects.

According to Dr. Jeffrey S. Dunham, an immunologist and researcher in 
Southern California, recent studies have determined that there are at least 
two distinct syndromes: one is the loss of fat related to the category of 
drugs including D4T, 3TC, DDI and AZT and the other occurs in patients using 
those drugs and one or more protease inhibitors in their highly active 
anti-retroviral therapy (HAART) regimen. "In other words, if you take D4T 
and/or other drugs in that class, you risk losing fat in the face, arms and 
legs," he says. "Add a protease inhibitor and you risk getting fat in the 
belly as well." Over time, the wasting effect becomes more pronounced. Additio
nal side effects include fatigue, nausea, liver damage and lactic acidosis, 
an accumulation of lactic acid that can be fatal in extreme cases.

Partners Randy Wendelin and Tom Finan both live with the effects of 
lipodystrophy. Because they work out avidly at the gym, their experience of 
lipodystrophy is that it causes their bodies to look more toned and muscular 
rather than disproportionate. This is especially important to Wendelin, an 
actor. "Working out burns off fat everywhere, so that if your body fat is 
low, lipodystrophy makes you even leaner," he says. "It's not this terrible, 
tragic disease. I get hired because I have character in my face. Losing 
facial fat can make a man more handsome -- there is no one 'look.'"

Finan says that he has HIV-negative friends who will not date men who seem to 
be wasting. He himself was working at The Gap when he noticed he was losing 
weight. "My look began to change," he says. "I became very aware of it." 
Walking down the streets of Los Angeles or San Francisco, he says that he can 
tell who is living with the disease and who isn't. "The look is a very drawn 
and hollow look," he says. "Once you have it, you can identify it in other 
people, but it can be cosmetically reversed."

One doctor who specializes in such reversals is Seth Matarasso, associate 
clinical professor of dermatology at UCSF. He is mindful to discuss loss of 
facial fat as a function of aging as well as disease and treatment. "As an 
immuno-compromised person, one does get facial wasting," he says, "But facial 
wasting is very common as we age. What we are used to seeing is skin lying on 
fat and muscle. When you have facial fat atrophying, you have skin lying on 
muscle. This can be very disfiguring, very disheartening for people with HIV."

Matarasso contends that proactive measures to counter lipodystrophy are out 
of reach until physicians have a greater understanding of its precise causes. 
Until then, he says, those wanting to restore their appearance can use a 
variety of cosmetic options, including facelifts, which soften depressions in 
the face, and soft-tissue augmentations, using gortex (synthetic fiber) or 
silicone implants, collagen injections and recycling one's own body fat.

A new and increasingly popular form of soft-tissue augmentation involves the 
harvesting of connective human muscular tissue called fascia, which is then 
made into a semi-solid substance called fascian that can be injected into the 
skin to plump it up. "It's not for everybody," says Matarasso. "Some patients 
have bruising, some have swelling. I simply don't know how long it will last. 
Done over a series of times, a patient can build up a reservoir, so there's 
more of a 'take.'" And then there's the cost: charges can be as much as $300 
to $400 per syringe of fascian and Matarasso sometimes recommends two 
syringes per treatment to ensure the desired effect lasts longer.

While Matarasso advises that fascian is no miracle or fountain of youth, he 
observes that cosmetic treatments do help patients feel better about their 
appearance, even as they feel healthier overall. "We've seen the gay 
community wasted by HIV/AIDS and it's a terrible, terrible burden," he says. 
"We've come so far and now we are dealing with some of the changes in coping 
with the disease. Many men feel great -- their T-cells are up, they're 
working out, they're able to go back to work. But they are watching their 
faces change before their eyes. It can be a physical stigma."

Both Wendelin and Finan opted for fascian injections performed by Matarasso 
and report their pleasure with the results. Cecilia Chung continues with her 
treatment interruption, though her somewhat increased viral load since coming 
off the meds has led her to consider resuming treatment. She is trying to 
postpone taking anti-retroviral drugs for as long as possible, though she is 
well aware of their benefits. The dilemma she faces is a common one among 
people living with HIV/AIDS and on medications: drug therapy can restore a 
large measure of health, but often at the expense of one's appearance and 
sense of normalcy. "If not for [the drugs], I don't think I would enjoy the 
health that I have now," she says. "before I started taking them, I was 
suffering with chronic fatigue syndrome. Since taking them, my health has 
gotten better and [I can now] work full time. But all the side effects are 
very difficult to deal with."

If the effects of lipodystrophy are hard to cope with, part of the reason is 
that appearance and our attachment to the way we look is more than skin-deep. 
Just as fat, tissue and muscle lie beneath our faces, layers of emotion -- 
pride, anxiety, fear -- can be concealed by the image we project to the rest 
of the world. If we live long enough, each of us will have to negotiate those 
empty spaces below the surface, finding or making fullness in spite of all 
that seems hollow, whether we are HIV positive or not.

=====

Letters to the Editor
Bay Area Reporter
June 10, 1999

Why cover ACT UP/SF?

I've been a gay activist since the early 1970s when I moved to San Francisco 
at the age of 18. I am concerned about the objectivity of your ongoing 
coverage of Michael Petrelis, David Pasquarelli, and ACT UP/SF.

I feel that your obvious hatred of Pat Christen and the San Francisco AIDS 
Foundation is influencing your coverage and over-exposure of these dangerous 
fringe fanatics. Regardless of your opinion of Pat Christen and the 
foundation, must you give legitimacy to these troubled anarchists just 
because you share a common hate?

Please think of the health and welfare of the community. By constantly giving 
them a forum they are able to perpetuate their ignorant misinformation. For 
example:

-- That HIV doesn't cause AIDS;

-- PWAs should stop taking their medication;

-- Barebacking is good;

-- Safe sex is tyrannical.

Most of the gay men I know think these ideas are ridiculous and dangerous, 
why not cover them?

Also the initiative proposed by these jerks to "reopen the bathhouses" is a 
cynical publicity stunt to gain more recognition and is also a red herring. 
We already have open bathhouses, they are sex clubs with showers which 
currently operate. What they want is completely unregulated public 
establishments with locked doors. You don't have to be a sociologist to 
deduce that with drug use on the rise, coupled with normal human male sexual 
behavior, this will lead to more unsafe sex and thus increase STDs, including 
AIDS, some of which will be resistant to current therapies. The Health 
Department has data to back this up, also it's just common sense. Haven't we 
learned anything? This is political suicide. It is a divisive ballot 
initiative that will never pass a general election. All that it will do is 
make our gay male community look like selfish hedonists, thus giving further 
ammunition to the radical religious right.

Randy Wendelin
San Francisco

=====

ACT UP San Francisco
1884 Market Street * San Francisco, CA 94102
Phone: (415) 864-6686 * Fax: (415) 864-6687 * www.actupsf.com

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